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N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic ß-cells.
Nord, Joshua A; Wynia-Smith, Sarah L; Gehant, Alyssa L; Jones Lipinski, Rachel A; Naatz, Aaron; Rioja, Inmaculada; Prinjha, Rab K; Corbett, John A; Smith, Brian C.
Affiliation
  • Nord JA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Wynia-Smith SL; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Gehant AL; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Jones Lipinski RA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Naatz A; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Rioja I; Immuno-Epigenetics, Immunology Research Unit, GlaxoSmithKline Medicines Research Centre, Stevenage, United Kingdom.
  • Prinjha RK; Immuno-Epigenetics, Immunology Research Unit, GlaxoSmithKline Medicines Research Centre, Stevenage, United Kingdom.
  • Corbett JA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Smith BC; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
Front Endocrinol (Lausanne) ; 13: 923925, 2022.
Article in En | MEDLINE | ID: mdl-36176467

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Diabetes Mellitus, Type 1 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Front Endocrinol (Lausanne) Year: 2022 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Diabetes Mellitus, Type 1 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Front Endocrinol (Lausanne) Year: 2022 Document type: Article Affiliation country: Estados Unidos