Biopolymer Filament Entanglement Softens Then Hardens with Shear.
Phys Rev Lett
; 129(14): 147801, 2022 Sep 30.
Article
in En
| MEDLINE
| ID: mdl-36240408
ABSTRACT
It is unsatisfactory that regarding the problem of entangled macromolecules driven out of equilibrium, experimentally based understanding is usually inferred from the ensemble average of polydisperse samples. Here, confronting with single-molecule imaging this common but poorly understood situation, over a wide range of shear rate we use single-molecule fluorescence imaging to track alignment and stretching of entangled aqueous filamentous actin filaments in a homebuilt rheo-microscope. With increasing shear rate, tube "softening" is followed by "hardening." Physically, this means that dynamical localization first weakens from molecular alignment, then strengthens from filament stretching, even for semiflexible biopolymers shorter than their persistence length.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Actin Cytoskeleton
/
Actins
Language:
En
Journal:
Phys Rev Lett
Year:
2022
Document type:
Article