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Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability to probe its latency transition.
Haynes, Laura M; Huttinger, Zachary M; Yee, Andrew; Kretz, Colin A; Siemieniak, David R; Lawrence, Daniel A; Ginsburg, David.
Affiliation
  • Haynes LM; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
  • Huttinger ZM; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Yee A; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
  • Kretz CA; Department of Medicine, McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada.
  • Siemieniak DR; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA; Howard Hughes Medical Institute.
  • Lawrence DA; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Ginsburg D; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, Michigan, USA; Howard Hughes Medical Institute; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Mich
J Biol Chem ; 298(12): 102608, 2022 12.
Article in En | MEDLINE | ID: mdl-36257408
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serpins / Plasminogen Activator Inhibitor 1 Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serpins / Plasminogen Activator Inhibitor 1 Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos