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IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling.
Goepfert, Arnaud; Barske, Carmen; Lehmann, Sylvie; Wirth, Emmanuelle; Willemsen, Joschka; Gudjonsson, Johann E; Ward, Nicole L; Sarkar, Mrinal K; Hemmig, René; Kolbinger, Frank; Rondeau, Jean-Michel.
Affiliation
  • Goepfert A; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland.
  • Barske C; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland.
  • Lehmann S; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland.
  • Wirth E; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland.
  • Willemsen J; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland.
  • Gudjonsson JE; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
  • Ward NL; Department of Dermatology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Sarkar MK; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
  • Hemmig R; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland.
  • Kolbinger F; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland.
  • Rondeau JM; Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4002 Basel, Switzerland. Electronic address: jeanmichel.rondeau@novartis.com.
Cell Rep ; 41(3): 111489, 2022 10 18.
Article in En | MEDLINE | ID: mdl-36260993
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-17 / Receptors, Interleukin-17 Limits: Humans Language: En Journal: Cell Rep Year: 2022 Document type: Article Affiliation country: Suiza
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-17 / Receptors, Interleukin-17 Limits: Humans Language: En Journal: Cell Rep Year: 2022 Document type: Article Affiliation country: Suiza