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Tackling the translational challenges of multi-omics research in the realm of European personalised medicine: A workshop report.
Oldoni, Emanuela; Saunders, Gary; Bietrix, Florence; Garcia Bermejo, Maria Laura; Niehues, Anna; 't Hoen, Peter A C; Nordlund, Jessica; Hajduch, Marian; Scherer, Andreas; Kivinen, Katja; Pitkänen, Esa; Mäkela, Tomi Pekka; Gut, Ivo; Scollen, Serena; Kozera, Lukasz; Esteller, Manel; Shi, Leming; Ussi, Anton; Andreu, Antonio L; van Gool, Alain J.
Affiliation
  • Oldoni E; European Infrastructure for Translational Medicine (EATRIS), Amsterdam, Netherlands.
  • Saunders G; European Infrastructure for Translational Medicine (EATRIS), Amsterdam, Netherlands.
  • Bietrix F; European Infrastructure for Translational Medicine (EATRIS), Amsterdam, Netherlands.
  • Garcia Bermejo ML; Biomarkers and Therapeutic Targets Group, Ramon and Cajal Health Research Institute (IRYCIS), Madrid, Spain.
  • Niehues A; Translational Metabolomic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
  • 't Hoen PAC; Center for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
  • Nordlund J; Center for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
  • Hajduch M; Department of Medical Sciences, Molecular Precision Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Scherer A; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Olomouc, Czechia.
  • Kivinen K; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Pitkänen E; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Mäkela TP; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.
  • Gut I; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
  • Scollen S; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
  • Kozera L; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.
  • Esteller M; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
  • Shi L; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.
  • Ussi A; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
  • Andreu AL; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • van Gool AJ; ELIXIR Hub, Hinxton, United Kingdom.
Front Mol Biosci ; 9: 974799, 2022.
Article in En | MEDLINE | ID: mdl-36310597
ABSTRACT
Personalised medicine (PM) presents a great opportunity to improve the future of individualised healthcare. Recent advances in -omics technologies have led to unprecedented efforts characterising the biology and molecular mechanisms that underlie the development and progression of a wide array of complex human diseases, supporting further development of PM. This article reflects the outcome of the 2021 EATRIS-Plus Multi-omics Stakeholder Group workshop organised to 1) outline a global overview of common promises and challenges that key European stakeholders are facing in the field of multi-omics research, 2) assess the potential of new technologies, such as artificial intelligence (AI), and 3) establish an initial dialogue between key initiatives in this space. Our focus is on the alignment of agendas of European initiatives in multi-omics research and the centrality of patients in designing solutions that have the potential to advance PM in long-term healthcare strategies.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Mol Biosci Year: 2022 Document type: Article Affiliation country: Países Bajos

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Mol Biosci Year: 2022 Document type: Article Affiliation country: Países Bajos