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Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiproliferative agents.
Mironov, Maksim E; Rybalova, Tatyana V; Pokrovskii, Mikhail A; Emaminia, Fatemeh; Gandalipov, Erik R; Pokrovskii, Andrey G; Shults, Elvira E.
Affiliation
  • Mironov ME; Laboratory of Medicinal Chemistry, Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, Novosibirsk 630090, Russian Federation; Novosibirsk State University, Pirogova Str. 2, Novosibirsk 630090, Russian Federation.
  • Rybalova TV; Laboratory of Medicinal Chemistry, Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, Novosibirsk 630090, Russian Federation.
  • Pokrovskii MA; Novosibirsk State University, Pirogova Str. 2, Novosibirsk 630090, Russian Federation.
  • Emaminia F; Novosibirsk State University, Pirogova Str. 2, Novosibirsk 630090, Russian Federation.
  • Gandalipov ER; International Institute of Solution Chemistry and Advanced Materials Technologies, ITMO University, 9 Lomonosov Street, 191002, Saint-Petersburg, Russian Federation.
  • Pokrovskii AG; Novosibirsk State University, Pirogova Str. 2, Novosibirsk 630090, Russian Federation.
  • Shults EE; Laboratory of Medicinal Chemistry, Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, Novosibirsk 630090, Russian Federation. Electronic address: schultz@nioch.nsc.ru.
Steroids ; 190: 109133, 2023 02.
Article in En | MEDLINE | ID: mdl-36328088
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diosgenin / Antineoplastic Agents Language: En Journal: Steroids Year: 2023 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diosgenin / Antineoplastic Agents Language: En Journal: Steroids Year: 2023 Document type: Article