Fetal Repair of Neural Tube Defects.
Clin Perinatol
; 49(4): 835-848, 2022 12.
Article
in En
| MEDLINE
| ID: mdl-36328602
ABSTRACT
Myelomeningocele is the most common congenital neurologic defect, and the only nonlethal disease addressed by fetal surgery. A randomized control trial has established amelioration of the Arnold-Chiari II malformation, reduced ventriculoperitoneal shunt rate, and improvement in distal neurologic function in patients that receive in utero repair. Long-term follow-up of these school-age children demonstrates the persistence of these effects. The use of stem cells in fetal repair is being investigated to further improve distal motor function.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Meningomyelocele
/
Fetal Therapies
/
Neural Tube Defects
Type of study:
Clinical_trials
Limits:
Child
/
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Clin Perinatol
Year:
2022
Document type:
Article