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Discovery of oxazoline enhancers of cellular progranulin release.
Peng, Xiaowen; Lanter, James C; Y-P Chen, Angela; Brand, Morgan A; Wozniak, Mary K; Hoekman, Steven; Longin, Ondrej; Regeling, Hendrik; Zonneveld, Wim; P L Bell, Roel; Koenig, Gerhard; Hurst, Raymond S; Blain, Jean-François; Burnett, Duane A.
Affiliation
  • Peng X; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA. Electronic address: xpeng@arkudatx.com.
  • Lanter JC; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
  • Y-P Chen A; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
  • Brand MA; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
  • Wozniak MK; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
  • Hoekman S; Symeres, Kerkenbos 1013, 6546 BB Nijmegen, the Netherlands.
  • Longin O; Symeres, Kerkenbos 1013, 6546 BB Nijmegen, the Netherlands.
  • Regeling H; Symeres, Kerkenbos 1013, 6546 BB Nijmegen, the Netherlands.
  • Zonneveld W; Symeres, Kerkenbos 1013, 6546 BB Nijmegen, the Netherlands.
  • P L Bell R; Symeres, Kerkenbos 1013, 6546 BB Nijmegen, the Netherlands.
  • Koenig G; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
  • Hurst RS; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
  • Blain JF; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
  • Burnett DA; Arkuda Therapeutics, 200 Arsenal Yards Blvd Suite 220, Watertown, MA 02472, USA.
Bioorg Med Chem Lett ; 80: 129048, 2023 01 15.
Article in En | MEDLINE | ID: mdl-36368496

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intercellular Signaling Peptides and Proteins / Frontotemporal Dementia Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intercellular Signaling Peptides and Proteins / Frontotemporal Dementia Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Country of publication: Reino Unido