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SFTS bunyavirus NSs protein sequestrates mTOR into inclusion bodies and deregulates mTOR-ULK1 signaling, provoking pro-viral autophagy.
Feng, Kuan; Zhang, Huijiao; Jiang, Zhenyu; Zhou, Min; Min, Yuan-Qin; Deng, Fei; Li, Peiqing; Wang, Hualin; Ning, Yun-Jia.
Affiliation
  • Feng K; State Key Laboratory of Virology and National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
  • Zhang H; Department of Pediatric Emergency, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Jiang Z; State Key Laboratory of Virology and National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
  • Zhou M; University of Chinese Academy of Sciences, Beijing, China.
  • Min YQ; State Key Laboratory of Virology and National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
  • Deng F; University of Chinese Academy of Sciences, Beijing, China.
  • Li P; State Key Laboratory of Virology and National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
  • Wang H; Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
  • Ning YJ; State Key Laboratory of Virology and National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
J Med Virol ; 95(1): e28371, 2023 01.
Article in En | MEDLINE | ID: mdl-36458534

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inclusion Bodies / Phlebovirus Limits: Humans Language: En Journal: J Med Virol Year: 2023 Document type: Article Affiliation country: China Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inclusion Bodies / Phlebovirus Limits: Humans Language: En Journal: J Med Virol Year: 2023 Document type: Article Affiliation country: China Country of publication: Estados Unidos