USP14 promotes pyroptosis of human annulus fibrosus cells derived from patients with intervertebral disc degeneration through deubiquitination of NLRP3.

Hai, Bao; Mao, Tianli; Du, Chuanchao; Jia, Fei; Liu, Yu; Song, Qingpeng; Pan, Xiaoyu; Liu, Xiaoguang; Zhu, Bin

Hai, Bao; Mao, Tianli; Du, Chuanchao; Jia, Fei; Liu, Yu; Song, Qingpeng; Pan, Xiaoyu; Liu, Xiaoguang; Zhu, Bin.

Affiliation

Hai B; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Mao T; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Du C; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Jia F; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Liu Y; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Song Q; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Pan X; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Liu X; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.
Zhu B; Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100191, China.

Acta Biochim Biophys Sin (Shanghai) ; 54(11): 1720 - 1730, 2022 11 25.

Article in En | MEDLINE | ID: mdl-36514221

Subject(s)
Key words

Intervertebral disc degeneration; NLRP3 inflammasome; USP14; deubiquitination; pyroptosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intervertebral Disc Degeneration / Annulus Fibrosus Limits: Humans Language: En Journal: Acta Biochim Biophys Sin (Shanghai) Journal subject: BIOFISICA / BIOQUIMICA Year: 2022 Document type: Article Affiliation country: China Country of publication: China

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