Power analysis for idiographic (within-subject) clinical trials: Implications for treatments of rare conditions and precision medicine.

Tueller, Stephen; Ramirez, Derek; Cance, Jessica D; Ye, Ai; Wheeler, Anne C; Fan, Zheng; Hornik, Christoph; Ridenour, Ty A

Tueller, Stephen; Ramirez, Derek; Cance, Jessica D; Ye, Ai; Wheeler, Anne C; Fan, Zheng; Hornik, Christoph; Ridenour, Ty A.

Affiliation

Tueller S; RTI International, 3040 E. Cornwallis Rd., PO Box 12194, 326 Cox Bldg, Research Triangle Park, NC, 27709-2194, USA.
Ramirez D; RTI International, 3040 E. Cornwallis Rd., PO Box 12194, 326 Cox Bldg, Research Triangle Park, NC, 27709-2194, USA.
Cance JD; RTI International, 3040 E. Cornwallis Rd., PO Box 12194, 326 Cox Bldg, Research Triangle Park, NC, 27709-2194, USA.
Ye A; University of North Carolina, Chapel Hill, Chapel Hill, NC, USA.
Wheeler AC; RTI International, 3040 E. Cornwallis Rd., PO Box 12194, 326 Cox Bldg, Research Triangle Park, NC, 27709-2194, USA.
Fan Z; University of North Carolina, Chapel Hill, Chapel Hill, NC, USA.
Hornik C; University of North Carolina, Chapel Hill, Chapel Hill, NC, USA.
Ridenour TA; Duke University, Durham, NC, 27708, USA.

Behav Res Methods ; 55(8): 4175-4199, 2023 12.

Article in En | MEDLINE | ID: mdl-36526885

Subject(s)
Key words

Effect size; Hierarchical modeling; Idiographic; Monte Carlo simulation; Piecewise regression; Precision medicine; Rare diseases; Statistical power; Within-subject clinical trials

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rare Diseases / Precision Medicine Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Behav Res Methods Journal subject: CIENCIAS DO COMPORTAMENTO Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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