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EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity.
Gabriel, Justus M; Tan, Thomas; Rinauro, Dillon J; Hsu, Claire M; Buettner, Caleb J; Gilmer, Marshall; Kaur, Amrita; McKenzie, Tristan L; Park, Martin; Cohen, Sophie; Errico, Silvia; Wright, Aidan K; Chiti, Fabrizio; Vendruscolo, Michele; Limbocker, Ryan.
Affiliation
  • Gabriel JM; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Tan T; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Rinauro DJ; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
  • Hsu CM; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Buettner CJ; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Gilmer M; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Kaur A; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • McKenzie TL; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Park M; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Cohen S; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Errico S; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy.
  • Wright AK; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA.
  • Chiti F; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy.
  • Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
  • Limbocker R; Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA. Electronic address: ryan.limbocker@westpoint.edu.
Chem Biol Interact ; 371: 110307, 2023 Feb 01.
Article in En | MEDLINE | ID: mdl-36535315

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Catechin / Melitten Limits: Animals Language: En Journal: Chem Biol Interact Year: 2023 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Catechin / Melitten Limits: Animals Language: En Journal: Chem Biol Interact Year: 2023 Document type: Article Affiliation country: Estados Unidos