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Structure-guided design and characterization of a clickable, covalent PARP16 inhibitor.
Bejan, Daniel S; Sundalam, Sunil; Jin, Haihong; Morgan, Rory K; Kirby, Ilsa T; Siordia, Ivan R; Tivon, Barr; London, Nir; Cohen, Michael S.
Affiliation
  • Bejan DS; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University Portland OR 97239 USA cohenmic@ohsu.edu.
  • Sundalam S; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University Portland OR 97239 USA cohenmic@ohsu.edu.
  • Jin H; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University Portland OR 97239 USA cohenmic@ohsu.edu.
  • Morgan RK; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University Portland OR 97239 USA cohenmic@ohsu.edu.
  • Kirby IT; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University Portland OR 97239 USA cohenmic@ohsu.edu.
  • Siordia IR; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University Portland OR 97239 USA cohenmic@ohsu.edu.
  • Tivon B; Department of Chemical and Structural Biology, The Weizmann Institute of Science Rehovot 7610001 Israel.
  • London N; Department of Chemical and Structural Biology, The Weizmann Institute of Science Rehovot 7610001 Israel.
  • Cohen MS; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University Portland OR 97239 USA cohenmic@ohsu.edu.
Chem Sci ; 13(46): 13898-13906, 2022 Nov 30.
Article in En | MEDLINE | ID: mdl-36544740
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Chem Sci Year: 2022 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Chem Sci Year: 2022 Document type: Article