Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2.

Guo, Xuanming; Cao, Jianli; Cai, Jian-Piao; Wu, Jiayan; Huang, Jiangang; Asthana, Pallavi; Wong, Sheung Kin Ken; Ye, Zi-Wei; Gurung, Susma; Zhang, Yijing; Wang, Sheng; Wang, Zening; Ge, Xin; Kwan, Hiu Yee; Lyu, Aiping; Chan, Kui Ming; Wong, Nathalie; Huang, Jiandong; Zhou, Zhongjun; Bian, Zhao-Xiang; Yuan, Shuofeng; Wong, Hoi Leong Xavier

Guo, Xuanming; Cao, Jianli; Cai, Jian-Piao; Wu, Jiayan; Huang, Jiangang; Asthana, Pallavi; Wong, Sheung Kin Ken; Ye, Zi-Wei; Gurung, Susma; Zhang, Yijing; Wang, Sheng; Wang, Zening; Ge, Xin; Kwan, Hiu Yee; Lyu, Aiping; Chan, Kui Ming; Wong, Nathalie; Huang, Jiandong; Zhou, Zhongjun; Bian, Zhao-Xiang; Yuan, Shuofeng; Wong, Hoi Leong Xavier.

Affiliation

Guo X; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Cao J; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Cai JP; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Wu J; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Huang J; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.
Asthana P; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Wong SKK; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Ye ZW; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Gurung S; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Zhang Y; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Wang S; Respiratory Department, Jinhua Guangfu Hospital, Jinhua, China.
Wang Z; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Ge X; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Kwan HY; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Lyu A; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Chan KM; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China.
Wong N; Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, N.T., Hong Kong SAR, China.
Huang J; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Zhou Z; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Bian ZX; Centre for Chinese Herbal Medicine Drug Development Limited, Hong Kong Baptist University, Hong Kong SAR, China.
Yuan S; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. yuansf@hku.hk.
Wong HLX; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. xavierwong@hkbu.edu.hk.

Nat Commun ; 13(1): 7907, 2022 12 23.

Article in En | MEDLINE | ID: mdl-36564389

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Matrix Metalloproteinase 14 / Host-Pathogen Interactions / Angiotensin-Converting Enzyme 2 / SARS-CoV-2 / COVID-19 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: China Country of publication: Reino Unido

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