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Geographically targeted chronic infection screening: lessons from a hepatitis B pilot study in the UK.
O'Ferrall, Angus M; MacElhinney-West, Alison; Bell, Mark S; Haslam, Michael P; Walker, Gemma; Norton, Donna; Burns, Sean A; Ferrier, Graham; Easom, Nicholas J W.
Affiliation
  • O'Ferrall AM; Infection Research Group, Hull University Teaching Hospitals - Address: Castle Hill Hospital, Castle Road, Cottingham, East Yorkshire, HU16 5JQ, UK.
  • MacElhinney-West A; Viral Hepatitis Service, Hull University Teaching Hospitals - Address: Castle Hill Hospital, Castle Road, Cottingham, East Yorkshire, HU16 5JQ, UK.
  • Bell MS; Viral Hepatitis Service, Hull University Teaching Hospitals - Address: Castle Hill Hospital, Castle Road, Cottingham, East Yorkshire, HU16 5JQ, UK.
  • Haslam MP; Viral Hepatitis Service, Hull University Teaching Hospitals - Address: Castle Hill Hospital, Castle Road, Cottingham, East Yorkshire, HU16 5JQ, UK.
  • Walker G; Infection Research Group, Hull University Teaching Hospitals - Address: Castle Hill Hospital, Castle Road, Cottingham, East Yorkshire, HU16 5JQ, UK.
  • Norton D; Infection Research Group, Hull University Teaching Hospitals - Address: Castle Hill Hospital, Castle Road, Cottingham, East Yorkshire, HU16 5JQ, UK.
  • Burns SA; The University of Sheffield - Address: Sheffield, S10 2TN, UK.
  • Ferrier G; Department of Geography, Geology and Environment, University of Hull - Address: Cottingham Road, Hull, HU6 7RX, UK.
  • Easom NJW; Infection Research Group, Hull University Teaching Hospitals - Address: Castle Hill Hospital, Castle Road, Cottingham, East Yorkshire, HU16 5JQ, UK.
Trans R Soc Trop Med Hyg ; 117(6): 403-406, 2023 06 02.
Article in En | MEDLINE | ID: mdl-36625250
ABSTRACT
Chronic hepatitis B (CHB) most commonly occurs following infection in early childhood. Prevalence varies markedly around the globe. Country of birth is therefore a strong predictor of CHB risk in adults. We used country of birth census data to predict CHB risk and carry out geographically targeted screening in East Yorkshire, UK. Despite engaging individuals born in high-prevalence countries with testing, we observed lower than expected prevalence in targeted highest-risk areas, which may indicate barriers to testing for people with undiagnosed CHB. Improved strategies for engagement with high-risk groups will be key for viral hepatitis elimination.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic / Hepatitis B Type of study: Diagnostic_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adult / Child, preschool / Humans Country/Region as subject: Europa Language: En Journal: Trans R Soc Trop Med Hyg Year: 2023 Document type: Article Affiliation country: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic / Hepatitis B Type of study: Diagnostic_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adult / Child, preschool / Humans Country/Region as subject: Europa Language: En Journal: Trans R Soc Trop Med Hyg Year: 2023 Document type: Article Affiliation country: Reino Unido