[Mutation of dentin sialophosphoprotein and hereditary malformations of dentin].
Zhonghua Kou Qiang Yi Xue Za Zhi
; 58(1): 17-24, 2023 Jan 09.
Article
in Zh
| MEDLINE
| ID: mdl-36642448
ABSTRACT
The classification as well as the clinical manifestations of hereditary malformations of dentin are of great concern and have been deeply elucidated. The understanding of its genetic basis also increases progressively. Dentin sialophosphoprotein (DSPP) is the pathogenic gene of dentinogenesis imperfecta type â
¡, dentinogenesis imperfecta type â
¢ and dentin dysplasia type â
¡. In this article, the classification of DSPP mutations as well as the resultant dysfunction of the mutant DSPP are summarized respectively and the corresponding clinical manifestations are analyzed. This work will provide a reference for the diagnosis and treatment of hereditary malformations of dentin.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dentinogenesis Imperfecta
Limits:
Humans
Language:
Zh
Journal:
Zhonghua Kou Qiang Yi Xue Za Zhi
Journal subject:
ODONTOLOGIA
Year:
2023
Document type:
Article
Affiliation country:
China
Publication country:
CHINA
/
CN
/
REPUBLIC OF CHINA