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Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene.
Kentistou, Katherine A; Luan, Jian'an; Wittemans, Laura B L; Hambly, Catherine; Klaric, Lucija; Kutalik, Zoltán; Speakman, John R; Wareham, Nicholas J; Kendall, Timothy J; Langenberg, Claudia; Wilson, James F; Joshi, Peter K; Morton, Nicholas M.
Affiliation
  • Kentistou KA; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, UK.
  • Luan J; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, UK.
  • Wittemans LBL; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Hambly C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Klaric L; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Kutalik Z; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, UK.
  • Speakman JR; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
  • Wareham NJ; Centre for Primary Care and Public Health, University of Lausanne, Lausanne, 1010, Switzerland.
  • Kendall TJ; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland.
  • Langenberg C; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, UK.
  • Wilson JF; Centre for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
  • Joshi PK; Shenzhen Key Laboratory of Metabolic Health, CAS Centre of Excellence in Animal Evolution and Genetics, Kunming, China.
  • Morton NM; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.
Nat Commun ; 14(1): 307, 2023 01 19.
Article in En | MEDLINE | ID: mdl-36658113
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adiposity / ADAMTS Proteins / Obesity Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adiposity / ADAMTS Proteins / Obesity Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido