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Metabolic Activation of Pesticide Isoprocarb Mediated by CYP3A4 and the Possible Correlation with Its Cytotoxicity.
Guan, Chunjing; Zhao, Guode; Sun, Chen; Zhang, Mingyu; Liu, Siyu; Jiang, Ziying; Li, Weiwei; Peng, Ying; Zheng, Jiang.
Affiliation
  • Guan C; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
  • Zhao G; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
  • Sun C; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
  • Zhang M; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
  • Liu S; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
  • Jiang Z; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
  • Li W; State Key Laboratory of Functions and Applications of Medicinal Plants, Key Laboratory of Pharmaceutics of Guizhou Province, Guizhou Medical University, Guiyang, Guizhou 550025, P. R. China.
  • Peng Y; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
  • Zheng J; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
J Agric Food Chem ; 71(5): 2390-2398, 2023 Feb 08.
Article in En | MEDLINE | ID: mdl-36706223
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carbamates / Microsomes, Liver / Cytochrome P-450 CYP3A / Chemical and Drug Induced Liver Injury / Activation, Metabolic Limits: Animals Language: En Journal: J Agric Food Chem Year: 2023 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carbamates / Microsomes, Liver / Cytochrome P-450 CYP3A / Chemical and Drug Induced Liver Injury / Activation, Metabolic Limits: Animals Language: En Journal: J Agric Food Chem Year: 2023 Document type: Article Country of publication: Estados Unidos