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Senescent stroma induces nuclear deformations in cancer cells via the inhibition of RhoA/ROCK/myosin II-based cytoskeletal tension.
Aifuwa, Ivie; Kim, Byoung Choul; Kamat, Pratik; Starich, Bartholomew; Agrawal, Anshika; Tanrioven, Derin; Luperchio, Teresa R; Valencia, Angela M Jimenez; Perestrelo, Tania; Reddy, Karen; Ha, Taekjip; Philip, Jude M.
Affiliation
  • Aifuwa I; Johns Hopkins Physical Sciences - Oncology Center, Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Kim BC; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Kamat P; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Starich B; Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Agrawal A; Division of Nano-Bioengineering, Incheon National University, Incheon 22012, South Korea.
  • Tanrioven D; Johns Hopkins Physical Sciences - Oncology Center, Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Luperchio TR; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Valencia AMJ; Johns Hopkins Physical Sciences - Oncology Center, Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Perestrelo T; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Reddy K; Johns Hopkins Physical Sciences - Oncology Center, Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Ha T; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Philip JM; Johns Hopkins Physical Sciences - Oncology Center, Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
PNAS Nexus ; 2(1): pgac270, 2023 Jan.
Article in En | MEDLINE | ID: mdl-36712940
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: PNAS Nexus Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: PNAS Nexus Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido