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A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein.
Yahiya, Sabrina; Saunders, Charlie N; Hassan, Sarah; Straschil, Ursula; Fischer, Oliver J; Rueda-Zubiaurre, Ainoa; Haase, Silvia; Vizcay-Barrena, Gema; Famodimu, Mufuliat Toyin; Jordan, Sarah; Delves, Michael J; Tate, Edward W; Barnard, Anna; Fuchter, Matthew J; Baum, Jake.
Affiliation
  • Yahiya S; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Saunders CN; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Hassan S; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK.
  • Straschil U; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK.
  • Fischer OJ; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Rueda-Zubiaurre A; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK.
  • Haase S; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK.
  • Vizcay-Barrena G; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Famodimu MT; Centre for Ultrastructural Imaging, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.
  • Jordan S; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Delves MJ; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Tate EW; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Barnard A; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK.
  • Fuchter MJ; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK.
  • Baum J; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK.
Dis Model Mech ; 16(2)2023 02 01.
Article in En | MEDLINE | ID: mdl-36715290
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium / Malaria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2023 Document type: Article Affiliation country: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium / Malaria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2023 Document type: Article Affiliation country: Reino Unido