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Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids.
Yousef Yengej, Fjodor A; Jansen, Jitske; Ammerlaan, Carola M E; Dilmen, Emre; Pou Casellas, Carla; Masereeuw, Rosalinde; Hoenderop, Joost G; Smeets, Bart; Rookmaaker, Maarten B; Verhaar, Marianne C; Clevers, Hans.
Affiliation
  • Yousef Yengej FA; Hubrecht Institute for Developmental Biology and Stem Cell Research - Royal Netherlands Academy of Arts and Sciences (KNAW) & University Medical Center Utrecht, 3584 CT and 3584 CX Utrecht, Netherlands.
  • Jansen J; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands.
  • Ammerlaan CME; Department of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA 6525 Nijmegen, The Netherlands.
  • Dilmen E; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Amalia Children's Hospital, GA 6525 Nijmegen, The Netherlands.
  • Pou Casellas C; Institute of Experimental Medicine and Systems Biology, Rheinisch-Westfälische Technische Hogeschool (RWTH) Aachen University, 52074 Aachen, Germany.
  • Masereeuw R; Hubrecht Institute for Developmental Biology and Stem Cell Research - Royal Netherlands Academy of Arts and Sciences (KNAW) & University Medical Center Utrecht, 3584 CT and 3584 CX Utrecht, Netherlands.
  • Hoenderop JG; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands.
  • Smeets B; Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA 6525 Nijmegen, The Netherlands.
  • Rookmaaker MB; Hubrecht Institute for Developmental Biology and Stem Cell Research - Royal Netherlands Academy of Arts and Sciences (KNAW) & University Medical Center Utrecht, 3584 CT and 3584 CX Utrecht, Netherlands.
  • Verhaar MC; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands.
  • Clevers H; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, CG 3584 Utrecht, The Netherlands.
Proc Natl Acad Sci U S A ; 120(6): e2216836120, 2023 02 07.
Article in En | MEDLINE | ID: mdl-36724260
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Type of study: Guideline Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Document type: Article Affiliation country: Países Bajos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Type of study: Guideline Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Document type: Article Affiliation country: Países Bajos