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Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.
Zhang, Baoshan; Gorman, Jason; Kwon, Young D; Pegu, Amarendra; Chao, Cara W; Liu, Tracy; Asokan, Mangaiarkarasi; Bender, Michael F; Bylund, Tatsiana; Damron, Leland; Gollapudi, Deepika; Lei, Paula; Li, Yile; Liu, Cuiping; Louder, Mark K; McKee, Krisha; Olia, Adam S; Rawi, Reda; Schön, Arne; Wang, Shuishu; Yang, Eun Sung; Yang, Yongping; Carlton, Kevin; Doria-Rose, Nicole A; Shapiro, Lawrence; Seaman, Michael S; Mascola, John R; Kwong, Peter D.
Affiliation
  • Zhang B; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Gorman J; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Kwon YD; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Pegu A; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Chao CW; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Liu T; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Asokan M; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Bender MF; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Bylund T; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Damron L; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Gollapudi D; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Lei P; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Li Y; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Liu C; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Louder MK; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • McKee K; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Olia AS; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Rawi R; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Schön A; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.
  • Wang S; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Yang ES; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Yang Y; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Carlton K; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Doria-Rose NA; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Shapiro L; Department of Biochemistry, Columbia University, New York, NY, USA.
  • Seaman MS; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Mascola JR; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
  • Kwong PD; Vaccine Research Center, NIAID, National Institutes of Health, Bethesda, MD, USA.
MAbs ; 15(1): 2165390, 2023.
Article in En | MEDLINE | ID: mdl-36729903
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Antibodies, Bispecific Limits: Animals / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Antibodies, Bispecific Limits: Animals / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Document type: Article Affiliation country: Estados Unidos