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Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Mejdrová, Ivana; Dusek, Jan; Skach, Krystof; Stefela, Alzbeta; Skoda, Josef; Chalupský, Karel; Dohnalová, Klára; Pavkova, Ivona; Kronenberger, Thales; Rashidian, Azam; Smutná, Lucie; Duchoslav, Vojtech; Smutny, Tomas; Pávek, Petr; Nencka, Radim.
Affiliation
  • Mejdrová I; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Dusek J; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
  • Skach K; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Stefela A; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
  • Skoda J; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
  • Chalupský K; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Dohnalová K; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídenská 1083, 142 20 Prague, Czech Republic.
  • Pavkova I; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídenská 1083, 142 20 Prague, Czech Republic.
  • Kronenberger T; 1st Medical Faculty, Charles University, Katerinska 32, 112 08 Prague, Czech Republic.
  • Rashidian A; Faculty of Military Health Sciences, University of Defense, Trebeska 1575, 500 01 Hradec Kralove, Czech Republic.
  • Smutná L; Department of Internal Medicine VIII, University Hospital of Tübingen, 72076 Tübingen, Germany.
  • Duchoslav V; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, 70211 Kuopio, Finland.
  • Smutny T; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität, 72076 Tübingen, Germany.
  • Pávek P; Department of Internal Medicine VIII, University Hospital of Tübingen, 72076 Tübingen, Germany.
  • Nencka R; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
J Med Chem ; 66(4): 2422-2456, 2023 02 23.
Article in En | MEDLINE | ID: mdl-36756805
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Steroid / Constitutive Androstane Receptor Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: República Checa
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Steroid / Constitutive Androstane Receptor Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: República Checa