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A Critical Study on Acylating and Covalent Reversible Fragment Inhibitors of SARS-CoV-2 Main Protease Targeting the S1 Site with Pyridine.
Wamser, Rebekka; Pach, Szymon; Arkona, Christoph; Baumgardt, Morris; Aziz, Umer Bin Abdul; Hocke, Andreas C; Wolber, Gerhard; Rademann, Jörg.
Affiliation
  • Wamser R; Department of Biology, Chemistry and Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str.2+4, 14195, Berlin, Germany.
  • Pach S; Department of Biology, Chemistry and Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str.2+4, 14195, Berlin, Germany.
  • Arkona C; Department of Biology, Chemistry and Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str.2+4, 14195, Berlin, Germany.
  • Baumgardt M; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Aziz UBA; Department of Biology, Chemistry and Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str.2+4, 14195, Berlin, Germany.
  • Hocke AC; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Wolber G; Department of Biology, Chemistry and Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str.2+4, 14195, Berlin, Germany.
  • Rademann J; Department of Biology, Chemistry and Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str.2+4, 14195, Berlin, Germany.
ChemMedChem ; 18(9): e202200635, 2023 05 02.
Article in En | MEDLINE | ID: mdl-36812048
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2023 Document type: Article Affiliation country: Alemania Country of publication: Alemania
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2023 Document type: Article Affiliation country: Alemania Country of publication: Alemania