Socio-economic and ethnic disparities in childhood cancer survival, Yorkshire, UK.
Br J Cancer
; 128(9): 1710-1722, 2023 05.
Article
in En
| MEDLINE
| ID: mdl-36828871
ABSTRACT
BACKGROUND:
Establishing the existence of health inequalities remains a high research and policy agenda item in the United Kingdom. We describe ethnic and socio-economic differences in paediatric cancer survival, focusing specifically on the extent to which disparities have changed over a 20-year period.METHODS:
Cancer registration data for 2674 children (0-14 years) in Yorkshire were analysed. Five-year survival estimates by ethnic group (south Asian/non-south Asian) and Townsend deprivation fifths (I-V) were compared over time (1997-2016) for leukaemia, lymphoma, central nervous system (CNS) and other solid tumours. Hazard ratios (HR 95% CI) from adjusted Cox models quantified the joint effect of ethnicity and deprivation on mortality risk over time, framed through causal interpretation of the deprivation coefficient.RESULTS:
Increasing deprivation was associated with significantly higher risk of death for children with leukaemia (1.11 (1.03-1.20)) and all cancers between 1997 and 2001. While we observed a trend towards reducing differences in survival over time in this group, a contrasting trend was observed for CNS tumours whereby sizeable variation in outcome remained for cases diagnosed until 2012. South Asian children with lymphoma had a 15% reduced chance of surviving at least 5 years compared to non-south Asian, across the study period.DISCUSSION:
Even in the United Kingdom, with a universally accessible healthcare system, socio-economic and ethnic disparities in childhood cancer survival exist. Findings should inform where resources should be directed to provide all children with an equitable survival outcome following a cancer diagnosis.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Leukemia
/
Central Nervous System Neoplasms
Type of study:
Health_economic_evaluation
/
Prognostic_studies
Aspects:
Determinantes_sociais_saude
Limits:
Child
/
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Br J Cancer
Year:
2023
Document type:
Article
Affiliation country:
Reino Unido