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First-in-Human, Single- and Multiple-Ascending-Dose, Food-Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase-Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects.
Kropeit, Dirk; Bonsmann, Susanne; von Richter, Oliver; McCormick, David; Pausch, Jörg; Sumner, Melanie; Birkmann, Alexander; Zimmermann, Holger; Rübsamen-Schaeff, Helga.
Affiliation
  • Kropeit D; Aicuris Anti-infective Cures AG, Wuppertal, Germany.
  • Bonsmann S; Aicuris Anti-infective Cures AG, Wuppertal, Germany.
  • von Richter O; Global Clinical Development, Biopharmaceuticals, Hexal AG (A Sandoz Company), Holzkirchen, Germany.
  • McCormick D; Aicuris Anti-infective Cures AG (Retired), Wuppertal, Germany.
  • Pausch J; BioNTech SE, Mainz, Germany.
  • Sumner M; Aicuris Anti-infective Cures AG, Wuppertal, Germany.
  • Birkmann A; Aicuris Anti-infective Cures AG, Wuppertal, Germany.
  • Zimmermann H; Aicuris Anti-infective Cures AG, Wuppertal, Germany.
  • Rübsamen-Schaeff H; Aicuris Anti-infective Cures AG, Wuppertal, Germany.
Clin Pharmacol Drug Dev ; 12(7): 749-760, 2023 07.
Article in En | MEDLINE | ID: mdl-36860173
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Simplexvirus / DNA Primase Limits: Female / Humans / Male Language: En Journal: Clin Pharmacol Drug Dev Year: 2023 Document type: Article Affiliation country: Alemania
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Simplexvirus / DNA Primase Limits: Female / Humans / Male Language: En Journal: Clin Pharmacol Drug Dev Year: 2023 Document type: Article Affiliation country: Alemania