Interactomics in plant defence: progress and opportunities.
Mol Biol Rep
; 50(5): 4605-4618, 2023 May.
Article
in En
| MEDLINE
| ID: mdl-36920596
Interactomics is a branch of systems biology that deals with the study of protein-protein interactions and how these interactions influence phenotypes. Identifying the interactomes involved during host-pathogen interaction events may bring us a step closer to deciphering the molecular mechanisms underlying plant defence. Here, we conducted a systematic review of plant interactomics studies over the last two decades and found that while a substantial progress has been made in the field, plant-pathogen interactomics remains a less-travelled route. As an effort to facilitate the progress in this field, we provide here a comprehensive research pipeline for an in planta plant-pathogen interactomics study that encompasses the in silico prediction step to the validation step, unconfined to model plants. We also highlight four challenges in plant-pathogen interactomics with plausible solution(s) for each.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plants
/
Host-Pathogen Interactions
Type of study:
Prognostic_studies
/
Systematic_reviews
Language:
En
Journal:
Mol Biol Rep
Year:
2023
Document type:
Article
Affiliation country:
Malasia
Country of publication:
Países Bajos