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CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.
Paust, Hans-Joachim; Song, Ning; De Feo, Donatella; Asada, Nariaki; Tuzlak, Selma; Zhao, Yu; Riedel, Jan-Hendrik; Hellmig, Malte; Sivayoganathan, Amirrtavarshni; Peters, Anett; Kaffke, Anna; Borchers, Alina; Wenzel, Ulrich O; Steinmetz, Oliver M; Tiegs, Gisa; Meister, Elisabeth; Mack, Matthias; Kurts, Christian; von Vietinghoff, Sibylle; Lindenmeyer, Maja T; Hoxha, Elion; Stahl, Rolf A K; Huber, Tobias B; Bonn, Stefan; Meyer-Schwesinger, Catherine; Wiech, Thorsten; Turner, Jan-Eric; Becher, Burkhard; Krebs, Christian F; Panzer, Ulf.
Affiliation
  • Paust HJ; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Song N; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • De Feo D; Institute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.
  • Asada N; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Tuzlak S; Institute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.
  • Zhao Y; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Riedel JH; Institute of Medical Systems Biology, Center for Biomedical AI, Center for Molecular Neurobiology Hamburg, Hamburg 20246, Germany.
  • Hellmig M; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Sivayoganathan A; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Peters A; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Kaffke A; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Borchers A; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Wenzel UO; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Steinmetz OM; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Tiegs G; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Meister E; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf 20246, Germany.
  • Mack M; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Kurts C; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • von Vietinghoff S; Department of Nephrology, University Hospital Regensburg, Regensburg 93042, Germany.
  • Lindenmeyer MT; Institute of Molecular Medicine and Experimental Immunology, University Hospital Bonn, Bonn 53127, Germany.
  • Hoxha E; Nephrology Section, Medical Clinic 1, University Hospital Bonn, Bonn 53127, Germany.
  • Stahl RAK; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Huber TB; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Bonn S; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Meyer-Schwesinger C; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Wiech T; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Turner JE; Institute of Medical Systems Biology, Center for Biomedical AI, Center for Molecular Neurobiology Hamburg, Hamburg 20246, Germany.
  • Becher B; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Krebs CF; Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Panzer U; Institute of Pathology, Division of Nephropathology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
Sci Transl Med ; 15(687): eadd6137, 2023 03 15.
Article in En | MEDLINE | ID: mdl-36921033

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Granulocyte-Macrophage Colony-Stimulating Factor / Glomerulonephritis Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2023 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Granulocyte-Macrophage Colony-Stimulating Factor / Glomerulonephritis Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2023 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos