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Pre-existing TGF-ß-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy.
Mortensen, Rasmus Erik Johansson; Holmström, Morten Orebo; Lisle, Thomas Landkildehus; Hasselby, Jane P; Willemoe, Gro L; Met, Özcan; Marie Svane, Inge; Johansen, Julia; Nielsen, Dorte L; Chen, Inna M; Andersen, Mads Hald.
Affiliation
  • Mortensen REJ; National Center for Cancer Immune Therapy, Department of Oncology, Herlev Hospital, Herlev, Denmark.
  • Holmström MO; National Center for Cancer Immune Therapy, Department of Oncology, Herlev Hospital, Herlev, Denmark.
  • Lisle TL; Department of Immunology and Microbiology, Copenhagen University, Copenhagen, Denmark.
  • Hasselby JP; National Center for Cancer Immune Therapy, Department of Oncology, Herlev Hospital, Herlev, Denmark.
  • Willemoe GL; Department of Pathology, Rigshospitalet, Copenhagen, Denmark.
  • Met Ö; Department of Pathology, Rigshospitalet, Copenhagen, Denmark.
  • Marie Svane I; National Center for Cancer Immune Therapy, Department of Oncology, Herlev Hospital, Herlev, Denmark.
  • Johansen J; National Center for Cancer Immune Therapy, Department of Oncology, Herlev Hospital, Herlev, Denmark.
  • Nielsen DL; Department of Oncology, Herlev Hospital, Herlev, Denmark.
  • Chen IM; Department of Oncology, Herlev Hospital, Herlev, Denmark.
  • Andersen MH; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
J Immunother Cancer ; 11(3)2023 03.
Article in En | MEDLINE | ID: mdl-36948507

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / T-Lymphocytes / Cancer Vaccines / Immune Checkpoint Inhibitors / Immunity, Cellular Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Immunother Cancer Year: 2023 Document type: Article Affiliation country: Dinamarca Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / T-Lymphocytes / Cancer Vaccines / Immune Checkpoint Inhibitors / Immunity, Cellular Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Immunother Cancer Year: 2023 Document type: Article Affiliation country: Dinamarca Country of publication: Reino Unido