Concurrent Living Donor Liver Transplantation and Off-Pump Coronary Artery Bypass in a Five-Year-Old Child With Homozygous Familial Hypercholesterolemia: A Case Report.
Transplant Proc
; 55(3): 676-679, 2023 Apr.
Article
in En
| MEDLINE
| ID: mdl-36967336
ABSTRACT
BACKGROUND:
Homozygous familial hypercholesterolemia (FH) is a rare disease that causes serious cardiovascular problems and may be fatal even at an early age. Because this disease variant is rather aggressive, the effect of lipid-lowering agents and lipid apheresis remains inadequate in most cases. In patients who are not responding or tolerating available treatments, liver transplantation (LT) is the last and definitive solution. In addition to LT, the need for cardiac surgery is often substantial. CASE REPORT This study presents the first pediatric case of FH who underwent off-pump coronary artery bypass (OPCAB) surgery concurrent with live-donor LT (LDLT). The early postoperative period was uneventful. After a 1-year follow-up period, the patient is alive and well with normal liver functions and cholesterol levels remaining within the normal range without any lipid-lowering medical therapy.CONCLUSION:
Performing simultaneous coronary bypass and LT may be safe and feasible even for pediatric patients.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Liver Transplantation
/
Coronary Artery Bypass, Off-Pump
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Homozygous Familial Hypercholesterolemia
/
Hyperlipoproteinemia Type II
Limits:
Child
/
Child, preschool
/
Humans
Language:
En
Journal:
Transplant Proc
Year:
2023
Document type:
Article
Affiliation country:
Azerbaiyán
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA