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Morusinol extracted from Morus alba induces cell cycle arrest and apoptosis via inhibition of DNA damage response in melanoma by CHK1 degradation through the ubiquitin-proteasome pathway.
Guo, Leiyang; Dong, Zhen; Zhang, Xiaolin; Yang, Yuanmiao; Hu, Xiaosong; Ji, Yacong; Li, Chongyang; Wan, Sicheng; Xu, Jie; Liu, Chaolong; Zhang, Yanli; Liu, Lichao; Shi, Yaqiong; Wu, Zonghui; Liu, Yaling; Cui, Hongjuan.
Affiliation
  • Guo L; Department of Dermatology, The Third Hospital of Hebei Medical University, 050000, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei 050051, China; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest Un
  • Dong Z; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China; Hospital of Southwest University, Medical Research Institute, Southwest University, Chongqing 400716, China; Engineering
  • Zhang X; Hospital of Southwest University, Medical Research Institute, Southwest University, Chongqing 400716, China.
  • Yang Y; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China.
  • Hu X; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China.
  • Ji Y; Department of Dermatology, The Third Hospital of Hebei Medical University, 050000, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei 050051, China.
  • Li C; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China.
  • Wan S; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China.
  • Xu J; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China.
  • Liu C; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China.
  • Zhang Y; Department of Dermatology, The Third Hospital of Hebei Medical University, 050000, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei 050051, China.
  • Liu L; Department of Dermatology, The Third Hospital of Hebei Medical University, 050000, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei 050051, China.
  • Shi Y; Department of Dermatology, The Third Hospital of Hebei Medical University, 050000, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei 050051, China.
  • Wu Z; Hospital of Southwest University, Medical Research Institute, Southwest University, Chongqing 400716, China.
  • Liu Y; Department of Dermatology, The Third Hospital of Hebei Medical University, 050000, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei 050051, China. Electronic address: yzling_liu@126.com.
  • Cui H; State Key Laboratory of Resource Insects, Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Ministry of Education), Southwest University, Chongqing 400716, China; Hospital of Southwest University, Medical Research Institute, Southwest University, Chongqing 400716, China; Engineering
Phytomedicine ; 114: 154765, 2023 Jun.
Article in En | MEDLINE | ID: mdl-37004403
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteasome Endopeptidase Complex / Melanoma Limits: Animals / Humans Language: En Journal: Phytomedicine Journal subject: TERAPIAS COMPLEMENTARES Year: 2023 Document type: Article Country of publication: Alemania
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteasome Endopeptidase Complex / Melanoma Limits: Animals / Humans Language: En Journal: Phytomedicine Journal subject: TERAPIAS COMPLEMENTARES Year: 2023 Document type: Article Country of publication: Alemania