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Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis.
Lou, Tingting; Li, Annan; Xu, Houchao; Pan, Jingfeng; Xing, Baiying; Wu, Ruibo; Dickschat, Jeroen S; Yang, Donghui; Ma, Ming.
Affiliation
  • Lou T; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing 100191, China.
  • Li A; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing 100191, China.
  • Xu H; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany.
  • Pan J; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Xing B; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing 100191, China.
  • Wu R; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Dickschat JS; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany.
  • Yang D; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing 100191, China.
  • Ma M; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing 100191, China.
J Am Chem Soc ; 2023 Apr 05.
Article in En | MEDLINE | ID: mdl-37018048
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Am Chem Soc Year: 2023 Document type: Article Affiliation country: China Country of publication: Estados Unidos
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Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Am Chem Soc Year: 2023 Document type: Article Affiliation country: China Country of publication: Estados Unidos