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The antifungal metabolites from coculture of Aspergillus fumigatus and Alternaria alternata associated with Coffea arabica.
Wu, Ya-Mei; Yang, Xue-Qiong; Yang, Ya-Bin; Cai, Le; He, Fei-Fei; Ding, Zhong-Tao.
Affiliation
  • Wu YM; Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, People's Republic of China.
  • Yang XQ; Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, People's Republic of China.
  • Yang YB; Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, People's Republic of China.
  • Cai L; Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, People's Republic of China.
  • He FF; School of Agriculture, Yunnan University, Kunming, People's Republic of China.
  • Ding ZT; Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, People's Republic of China.
Nat Prod Res ; 38(5): 753-758, 2024.
Article in En | MEDLINE | ID: mdl-37021795
One new cyclohexenone derivative, asperfumtone A (1) along with six known compounds were obtained from the coculture of Aspergillus fumigatus and Alternaria alternata associated with Coffea arabica. The configuration of 2 was first reported in the research. The structures were determined by extensive spectroscopic analyses, and ECD calculation. Compounds 3, 4 and 7 showed significant antifungal activities against coffee phytopathogens A. alternata and Fusarium incarnatum with MICs of 1 µg/mL. Compounds 1 and 2 showed weak antifungal activities against A. alternata and F. incarnatum with MICs of 32-64 µg/mL.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspergillus fumigatus / Coffea Type of study: Risk_factors_studies Language: En Journal: Nat Prod Res Year: 2024 Document type: Article Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspergillus fumigatus / Coffea Type of study: Risk_factors_studies Language: En Journal: Nat Prod Res Year: 2024 Document type: Article Country of publication: Reino Unido