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Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2.
Li, Rui; Shao, Jingchen; Jin, Young-June; Kawase, Haruya; Ong, Yu Ting; Troidl, Kerstin; Quan, Qi; Wang, Lei; Bonnavion, Remy; Wietelmann, Astrid; Helmbacher, Francoise; Potente, Michael; Graumann, Johannes; Wettschureck, Nina; Offermanns, Stefan.
Affiliation
  • Li R; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Shao J; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Jin YJ; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Kawase H; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Ong YT; Max Planck Institute for Heart and Lung Research, Angiogenesis & Metabolism Laboratory, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Troidl K; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Quan Q; Department of Vascular and Endovascular Surgery, Cardiovascular Surgery Clinic, University Hospital Frankfurt and Wolfgang Goethe University Frankfurt, Frankfurt, Germany.
  • Wang L; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Bonnavion R; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Wietelmann A; Max Planck Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Helmbacher F; Max Planck Institute for Heart and Lung Research, Small Animal Imaging Service Group, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Potente M; Aix Marseille Université, CNRS, IBDM UMR 7288, Parc Scientifique de Luminy, Case 907, 13288, Marseille, France.
  • Graumann J; Max Planck Institute for Heart and Lung Research, Angiogenesis & Metabolism Laboratory, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
  • Wettschureck N; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, and Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Offermanns S; Max Planck Institute for Heart and Lung Research, Biomolecular Mass Spectrometry Service Group, Ludwigstr. 43, 61231, Bad Nauheim, Germany.
Nat Commun ; 14(1): 1980, 2023 04 08.
Article in En | MEDLINE | ID: mdl-37031213
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trans-Activators / Adaptor Proteins, Signal Transducing Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trans-Activators / Adaptor Proteins, Signal Transducing Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido