Neonatal Lymphatic Flow Disorder.
Indian J Pediatr
; 91(3): 248-253, 2024 Mar.
Article
in En
| MEDLINE
| ID: mdl-37040015
ABSTRACT
OBJECTIVE:
To examine and discuss patients diagnosed with acquired and congenital chylothorax in the neonatal period in the light of the literature.METHODS:
The files of newborns followed-up in the neonatal intensive care unit (NICU) and diagnosed with congenital and acquired chylothorax were reviewed retrospectively. Patients with isolated chylothorax were classified as Group 1 and those with multiple lymphatic flow disorders were classified as Group 2. Antenatal and clinical features were recorded and compared between the groups.RESULTS:
Thirteen infants were diagnosed with chylothorax; 92.3% (n = 12) of the patients were congenital. The rate of antenatal diagnosis was 61.5% (n = 8). Eight patients (61.5%) were diagnosed with hydrops fetalis. Among the cases in Group 1 and Group 2, receiving ocreotide and the incidence of sepsis (p = 0.05) were partially significant. Seven of the patients (66.6%) responded to medium chain triglycerides (MCT), and complete resolution was seen in 6 (85.7%) of the responders. Complete resolution of chylothorax fluid was observed in 7 (77.7%) of nine patients who responded to ocreotide treatment.CONCLUSIONS:
In neonatal chylothorax, the postnatal period includes a multidisciplinary approach that requires drug therapy, dietary modifications, drainage of pleural fluid, and rarely, surgery.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chylothorax
/
Infant, Newborn, Diseases
Limits:
Female
/
Humans
/
Infant
/
Newborn
/
Pregnancy
Language:
En
Journal:
Indian J Pediatr
Year:
2024
Document type:
Article
Affiliation country:
Turquía