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Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ-Secretase Modulator.
Chen, Xu-Qiao; Sawa, Mariko; Becker, Ann; Karachentsev, Dmitry; Zuo, Xinxin; Rynearson, Kevin D; Tanzi, Rudolph E; Mobley, William C.
Affiliation
  • Chen XQ; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
  • Sawa M; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
  • Becker A; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
  • Karachentsev D; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
  • Zuo X; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
  • Rynearson KD; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
  • Tanzi RE; Genetics and Aging Research Unit, McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
  • Mobley WC; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Ann Neurol ; 94(2): 245-258, 2023 08.
Article in En | MEDLINE | ID: mdl-37042072

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down Syndrome / Alzheimer Disease Limits: Animals / Humans Language: En Journal: Ann Neurol Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down Syndrome / Alzheimer Disease Limits: Animals / Humans Language: En Journal: Ann Neurol Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos