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Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Kiss, Leo; Rhinesmith, Tyler; Luptak, Jakub; Dickson, Claire F; Weidenhausen, Jonas; Smyly, Shannon; Yang, Ji-Chun; Maslen, Sarah L; Sinning, Irmgard; Neuhaus, David; Clift, Dean; James, Leo C.
Affiliation
  • Kiss L; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK. lkiss@biochem.mpg.de.
  • Rhinesmith T; Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152, Martinsried, Germany. lkiss@biochem.mpg.de.
  • Luptak J; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
  • Dickson CF; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
  • Weidenhausen J; EMBL Australia Node in Single Molecule Science and ARC Centre of Excellence in Advanced Molecular Imaging School of Medical Sciences, UNSW Sydney, NSW, 2052, Australia.
  • Smyly S; Biochemiezentrum der Universität Heidelberg (BZH), INF328, D-69120, Heidelberg, Germany.
  • Yang JC; EMBL Heidelberg, Meyerhofstraße 1, 69117, Heidelberg, Germany.
  • Maslen SL; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
  • Sinning I; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
  • Neuhaus D; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
  • Clift D; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • James LC; Biochemiezentrum der Universität Heidelberg (BZH), INF328, D-69120, Heidelberg, Germany.
Nat Commun ; 14(1): 2160, 2023 04 15.
Article in En | MEDLINE | ID: mdl-37061529
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Lysine Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Lysine Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Reino Unido