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The glucagon receptor antagonist desHis1Pro4Glu9-glucagon(Lys12PAL) alters alpha-cell turnover and lineage in mice, but does not cause alpha-cell hyperplasia.
Lafferty, Ryan; Tanday, Neil; Dubey, Vaibhav; Coulter-Parkhill, Aimee; Vishal, Karthick; Moffett, Charlotte; O'Harte, Finbarr; Flatt, Peter R; Irwin, Nigel.
Affiliation
  • Lafferty R; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • Tanday N; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • Dubey V; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • Coulter-Parkhill A; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • Vishal K; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • Moffett C; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • O'Harte F; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • Flatt PR; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
  • Irwin N; Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK. Electronic address: n.irwin@ulster.ac.uk.
Mol Cell Endocrinol ; 570: 111932, 2023 06 15.
Article in En | MEDLINE | ID: mdl-37080378

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Glucagon / Insulin Limits: Animals / Humans Language: En Journal: Mol Cell Endocrinol Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Irlanda

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Glucagon / Insulin Limits: Animals / Humans Language: En Journal: Mol Cell Endocrinol Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Irlanda