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Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation.
Ford, Kyle; Munson, Brenton P; Fong, Samson H; Panwala, Rebecca; Chu, Wai Keung; Rainaldi, Joseph; Plongthongkum, Nongluk; Arunachalam, Vinayagam; Kostrowicki, Jarek; Meluzzi, Dario; Kreisberg, Jason F; Jensen-Pergakes, Kristen; VanArsdale, Todd; Paul, Thomas; Tamayo, Pablo; Zhang, Kun; Bienkowska, Jadwiga; Mali, Prashant; Ideker, Trey.
Affiliation
  • Ford K; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Munson BP; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Fong SH; Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
  • Panwala R; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Chu WK; Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
  • Rainaldi J; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Plongthongkum N; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Arunachalam V; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Kostrowicki J; Biomedical Sciences Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Meluzzi D; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Kreisberg JF; Pfizer Inc, 10555 Science Center Drive, San Diego, CA, 92121, USA.
  • Jensen-Pergakes K; Pfizer Inc, 10555 Science Center Drive, San Diego, CA, 92121, USA.
  • VanArsdale T; Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
  • Paul T; Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
  • Tamayo P; Pfizer Inc, 10555 Science Center Drive, San Diego, CA, 92121, USA.
  • Zhang K; Pfizer Inc, 10555 Science Center Drive, San Diego, CA, 92121, USA.
  • Bienkowska J; Pfizer Inc, 10555 Science Center Drive, San Diego, CA, 92121, USA.
  • Mali P; Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
  • Ideker T; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Sci Rep ; 13(1): 7678, 2023 05 11.
Article in En | MEDLINE | ID: mdl-37169829
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Sci Rep Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Sci Rep Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido