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Mechanism of rotenone binding to respiratory complex I depends on ligand flexibility.
Pereira, Caroline S; Teixeira, Murilo H; Russell, David A; Hirst, Judy; Arantes, Guilherme M.
Affiliation
  • Pereira CS; Department of Biochemistry, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, São Paulo, SP, 05508-900, Brazil.
  • Teixeira MH; Department of Biochemistry, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, São Paulo, SP, 05508-900, Brazil.
  • Russell DA; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
  • Hirst J; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK. jh@mrc-mbu.cam.ac.uk.
  • Arantes GM; Department of Biochemistry, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, São Paulo, SP, 05508-900, Brazil. garantes@iq.usp.br.
Sci Rep ; 13(1): 6738, 2023 04 25.
Article in En | MEDLINE | ID: mdl-37185607
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rotenone / Electron Transport Complex I Language: En Journal: Sci Rep Year: 2023 Document type: Article Affiliation country: Brasil Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rotenone / Electron Transport Complex I Language: En Journal: Sci Rep Year: 2023 Document type: Article Affiliation country: Brasil Country of publication: Reino Unido