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Synthesis and Preclinical Evaluation of 2-(4-[18F]Fluorophenyl)imidazo[1,2-h][1,7]naphthyridine ([18F]FPND-4): An Aza-Fused Tricyclic Derivative as Positron Emission Tomography Tracer for Neurofibrillary Tangle Imaging.
Liu, Tianqing; Li, Yuying; Zhang, Xiaojun; Yao, An; Wang, Yan; Yao, Shulin; Chen, Baian; Yan, Xiao-Xin; Dai, Jiapei; Zhang, Jinming; Cui, Mengchao.
Affiliation
  • Liu T; Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Li Y; Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Zhang X; Department of Nuclear Medicine, Chinese PLA General Hospital, Beijing 100853, China.
  • Yao A; Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
  • Wang Y; Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha 410013, China.
  • Yao S; Department of Nuclear Medicine, Chinese PLA General Hospital, Beijing 100853, China.
  • Chen B; School of Basic Medical Sciences, Beijing Key Laboratory of Neural Regeneration and Repair, Capital Medical University, Beijing, 100069, China.
  • Yan XX; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
  • Dai J; Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha 410013, China.
  • Zhang J; Wuhan Institute for Neuroscience and Neuroengineering, South-Central Minzu University, Wuhan 430074, China.
  • Cui M; Department of Nuclear Medicine, Chinese PLA General Hospital, Beijing 100853, China.
J Med Chem ; 66(14): 9561-9576, 2023 07 27.
Article in En | MEDLINE | ID: mdl-37199108
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurofibrillary Tangles / Alzheimer Disease Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: China Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurofibrillary Tangles / Alzheimer Disease Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: China Country of publication: Estados Unidos