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The Mycobacterium tuberculosis protein tyrosine phosphatase MptpA features a pH dependent activity overlapping the bacterium sensitivity to acidic conditions.
Kovermann, Michael; Stefan, Alessandra; Palazzetti, Chiara; Immler, Fabian; Dal Piaz, Fabrizio; Bernardi, Luca; Cimone, Valentina; Bellone, Maria Laura; Hochkoeppler, Alejandro.
Affiliation
  • Kovermann M; Department of Chemistry, University of Konstanz, Universitätstraße 10, 78464, Konstanz, Germany.
  • Stefan A; Department of Pharmacy and Biotechnology, University of Bologna, Viale Risorgimento 4, 40136, Bologna, Italy; CSGI, University of Florence, Via della Lastruccia 3, 50019, Sesto Fiorentino, Firenze, Italy.
  • Palazzetti C; Department of Pharmacy and Biotechnology, University of Bologna, Viale Risorgimento 4, 40136, Bologna, Italy.
  • Immler F; Department of Chemistry, University of Konstanz, Universitätstraße 10, 78464, Konstanz, Germany.
  • Dal Piaz F; Department of Medicine, University of Salerno, Via Giovanni Paolo II 132, 84084, Fisciano, Italy.
  • Bernardi L; Department of Industrial Chemistry "Toson Montanaro", University of Bologna, Viale Risorgimento 4, 40136, Bologna, Italy.
  • Cimone V; Department of Pharmacy and Biotechnology, University of Bologna, Viale Risorgimento 4, 40136, Bologna, Italy.
  • Bellone ML; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084, Fisciano, Italy.
  • Hochkoeppler A; Department of Pharmacy and Biotechnology, University of Bologna, Viale Risorgimento 4, 40136, Bologna, Italy; CSGI, University of Florence, Via della Lastruccia 3, 50019, Sesto Fiorentino, Firenze, Italy. Electronic address: a.hochkoeppler@unibo.it.
Biochimie ; 213: 66-81, 2023 Oct.
Article in En | MEDLINE | ID: mdl-37201648
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Mycobacterium tuberculosis Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Biochimie Year: 2023 Document type: Article Affiliation country: Alemania
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Mycobacterium tuberculosis Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Biochimie Year: 2023 Document type: Article Affiliation country: Alemania