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Flucloxacillin Is a Weak Inducer of CYP3A4 in Healthy Adults and 3D Spheroid of Primary Human Hepatocytes.
Iversen, Ditte B; Dunvald, Ann-Cathrine Dalgård; Jespersen, Daniel M; Nielsen, Flemming; Brøsen, Kim; Damkier, Per; Hammer, Helen S; Pötz, Oliver; Järvinen, Erkka; Stage, Tore B.
Affiliation
  • Iversen DB; Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.
  • Dunvald AD; Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.
  • Jespersen DM; Otterup Pharmacy, Otterup, Denmark.
  • Nielsen F; Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.
  • Brøsen K; Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.
  • Damkier P; Department of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.
  • Hammer HS; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
  • Pötz O; Signatope GmbH, Reutlingen, Germany.
  • Järvinen E; Signatope GmbH, Reutlingen, Germany.
  • Stage TB; NMI Natural and Medical Sciences Institute at the University of Tuebingen, Reutlingen, Germany.
Clin Pharmacol Ther ; 114(2): 434-445, 2023 08.
Article in En | MEDLINE | ID: mdl-37235733

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP3A / Floxacillin Type of study: Clinical_trials Limits: Adult / Humans Language: En Journal: Clin Pharmacol Ther Year: 2023 Document type: Article Affiliation country: Dinamarca Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP3A / Floxacillin Type of study: Clinical_trials Limits: Adult / Humans Language: En Journal: Clin Pharmacol Ther Year: 2023 Document type: Article Affiliation country: Dinamarca Country of publication: Estados Unidos