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Management of the Sickle Cell Trait: An Opinion by Expert Panel Members.
Pinto, Valeria Maria; De Franceschi, Lucia; Gianesin, Barbara; Gigante, Antonia; Graziadei, Giovanna; Lombardini, Letizia; Palazzi, Giovanni; Quota, Alessandra; Russo, Rodolfo; Sainati, Laura; Venturelli, Donatella; Forni, Gian Luca; Origa, Raffaella.
Affiliation
  • Pinto VM; Centro della Microcitemia, Anemie Congenite e Dismetabolismo del Ferro, E.O. Ospedali Galliera, 16128 Genova, Italy.
  • De Franceschi L; Dipartimento di Medicina AOUI, Università di Verona, 37124 Verona, Italy.
  • Gianesin B; Centro della Microcitemia, Anemie Congenite e Dismetabolismo del Ferro, E.O. Ospedali Galliera, 16128 Genova, Italy.
  • Gigante A; ForAnemia Foundation, 16124 Genova, Italy.
  • Graziadei G; ForAnemia Foundation, 16124 Genova, Italy.
  • Lombardini L; Società Italiana Talassemie ed Emoglobinopatie (SITE), 09100 Cagliari, Italy.
  • Palazzi G; Centro Malattie Rare Internistiche, Medicina Generale, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
  • Quota A; Centro Nazionale Trapianti, Istituto Superiore di Sanità, 00161 Roma, Italy.
  • Russo R; U.O. Oncoematologia Pediatrica, Azienda Ospedaliero-Universitaria di Modena, 41125 Modena, Italy.
  • Sainati L; UOSD Talassemia, P.O. Vittorio Emanuele, 93012 Gela, Italy.
  • Venturelli D; Clinica Nefrologica, Dialisi e Trapianto, Dipartimento di Medicina Integrata con il Territorio, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
  • Forni GL; Oncoematologia Pediatrica, Azienda Ospedaliera-Università di Padova, 35128 Padova, Italy.
  • Origa R; Servizio Immunotrasfusionale, Azienda Ospedaliero-Universitaria di Modena, 41125 Modena, Italy.
J Clin Med ; 12(10)2023 May 12.
Article in En | MEDLINE | ID: mdl-37240547
ABSTRACT
The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally. Because of the high frequency of sickle cell disease, reproductive counseling is of crucial importance. In addition, unlike other carrier states, Sickle Cell Trait (SCT) seems to be a risk factor for several clinical complications, such as extreme exertional injury, chronic kidney disease, and complications during pregnancy and surgery. This expert panel believes that increasing knowledge about these clinical manifestations and their prevention and management can be a useful tool for all healthcare providers involved in this issue.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Risk_factors_studies Language: En Journal: J Clin Med Year: 2023 Document type: Article Affiliation country: Italia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Risk_factors_studies Language: En Journal: J Clin Med Year: 2023 Document type: Article Affiliation country: Italia