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Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.
Adlam, David; Berrandou, Takiy-Eddine; Georges, Adrien; Nelson, Christopher P; Giannoulatou, Eleni; Henry, Joséphine; Ma, Lijiang; Blencowe, Montgomery; Turley, Tamiel N; Yang, Min-Lee; Chopade, Sandesh; Finan, Chris; Braund, Peter S; Sadeg-Sayoud, Ines; Iismaa, Siiri E; Kosel, Matthew L; Zhou, Xiang; Hamby, Stephen E; Cheng, Jenny; Liu, Lu; Tarr, Ingrid; Muller, David W M; d'Escamard, Valentina; King, Annette; Brunham, Liam R; Baranowska-Clarke, Ania A; Debette, Stéphanie; Amouyel, Philippe; Olin, Jeffrey W; Patil, Snehal; Hesselson, Stephanie E; Junday, Keerat; Kanoni, Stavroula; Aragam, Krishna G; Butterworth, Adam S; Tweet, Marysia S; Gulati, Rajiv; Combaret, Nicolas; Kadian-Dodov, Daniella; Kalman, Jonathan M; Fatkin, Diane; Hingorani, Aroon D; Saw, Jacqueline; Webb, Tom R; Hayes, Sharonne N; Yang, Xia; Ganesh, Santhi K; Olson, Timothy M; Kovacic, Jason C; Graham, Robert M.
Affiliation
  • Adlam D; Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK. da134@leicester.ac.uk.
  • Berrandou TE; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK. da134@leicester.ac.uk.
  • Georges A; Université Paris Cité, Paris Cardiovascular Research Center, Inserm, Paris, France.
  • Nelson CP; Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.
  • Giannoulatou E; Université Paris Cité, Paris Cardiovascular Research Center, Inserm, Paris, France.
  • Henry J; Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK.
  • Ma L; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
  • Blencowe M; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia.
  • Turley TN; School of Clinical Medicine, Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Yang ML; Université Paris Cité, Paris Cardiovascular Research Center, Inserm, Paris, France.
  • Chopade S; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Finan C; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Braund PS; Interdepartmental Program of Molecular, Cellular, and Integrative Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Sadeg-Sayoud I; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN, USA.
  • Iismaa SE; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Kosel ML; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Zhou X; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Hamby SE; Institute for Cardiovascular Science, University College London, London, UK.
  • Cheng J; British Heart Foundation Research Accelerator, University College London, London, UK.
  • Liu L; Institute for Cardiovascular Science, University College London, London, UK.
  • Tarr I; British Heart Foundation Research Accelerator, University College London, London, UK.
  • Muller DWM; Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK.
  • d'Escamard V; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
  • King A; Université Paris Cité, Paris Cardiovascular Research Center, Inserm, Paris, France.
  • Brunham LR; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia.
  • Baranowska-Clarke AA; School of Clinical Medicine, Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Debette S; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
  • Amouyel P; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Olin JW; Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK.
  • Patil S; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
  • Hesselson SE; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Junday K; Interdepartmental Program of Molecular, Cellular, and Integrative Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Kanoni S; Université Paris Cité, Paris Cardiovascular Research Center, Inserm, Paris, France.
  • Aragam KG; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia.
  • Butterworth AS; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia.
  • Tweet MS; Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Gulati R; Centre for Heart Lung Innovation, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Combaret N; Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK.
  • Kadian-Dodov D; Department of Neurology, Bordeaux University Hospital, Inserm, Bordeaux, France.
  • Kalman JM; Université de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, RID-AGE - Labex DISTALZ - Risk Factors and Molecular Determinants of Aging-Related Disease, Lille, France.
  • Fatkin D; Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Hingorani AD; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Saw J; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia.
  • Webb TR; School of Clinical Medicine, Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Hayes SN; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia.
  • Yang X; School of Clinical Medicine, Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Ganesh SK; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Olson TM; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Kovacic JC; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Graham RM; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nat Genet ; 55(6): 964-972, 2023 06.
Article in En | MEDLINE | ID: mdl-37248441
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vascular Diseases / Coronary Artery Disease / Myocardial Infarction Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2023 Document type: Article Affiliation country: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vascular Diseases / Coronary Artery Disease / Myocardial Infarction Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2023 Document type: Article Affiliation country: Reino Unido