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Targeted sequencing of cancer-related genes reveals a recurrent TOP2A variant which affects DNA binding and coincides with global transcriptional changes in glioblastoma.
Gielniewski, Bartlomiej; Poleszak, Katarzyna; Roura, Adria-Jaume; Szadkowska, Paulina; Jacek, Karol; Krol, Sylwia K; Guzik, Rafal; Wiechecka, Paulina; Maleszewska, Marta; Kaza, Beata; Marchel, Andrzej; Czernicki, Tomasz; Koziarski, Andrzej; Zielinski, Grzegorz; Styk, Andrzej; Kawecki, Maciej; Szczylik, Cezary; Czepko, Ryszard; Banach, Mariusz; Kaspera, Wojciech; Szopa, Wojciech; Bujko, Mateusz; Czapski, Bartosz; Zabek, Miroslaw; Izycka-Swieszewska, Ewa; Kloc, Wojciech; Nauman, Pawel; Cieslewicz, Joanna; Grajkowska, Wieslawa; Morosini, Natalia; Noushmehr, Houtan; Wojtas, Bartosz; Kaminska, Bozena.
Affiliation
  • Gielniewski B; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Poleszak K; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Roura AJ; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Szadkowska P; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Jacek K; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Krol SK; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Guzik R; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Wiechecka P; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Maleszewska M; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Kaza B; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
  • Marchel A; Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland.
  • Czernicki T; Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland.
  • Koziarski A; Department of Neurosurgery, Military Institute of Medicine, Warsaw, Poland.
  • Zielinski G; Department of Neurosurgery, Military Institute of Medicine, Warsaw, Poland.
  • Styk A; Department of Neurosurgery, Military Institute of Medicine, Warsaw, Poland.
  • Kawecki M; Department of Oncology, Military Institute of Medicine, Warsaw, Poland.
  • Szczylik C; The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Czepko R; Department of Oncology, Military Institute of Medicine, Warsaw, Poland.
  • Banach M; Department of Neurosurgery, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland.
  • Kaspera W; Department of Neurosurgery, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland.
  • Szopa W; Department of Neurosurgery, Medical University of Silesia, Regional Hospital, Sosnowiec, Poland.
  • Bujko M; Department of Neurosurgery, Medical University of Silesia, Regional Hospital, Sosnowiec, Poland.
  • Czapski B; The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Zabek M; Department of Neurosurgery, Mazovian Brodnowski Hospital, Warsaw, Poland.
  • Izycka-Swieszewska E; Department of Neurosurgery, Mazovian Brodnowski Hospital, Warsaw, Poland.
  • Kloc W; Department of Neurosurgery and Nervous System Trauma, Centre of Postgraduate Medical Education, Warsaw, Poland.
  • Nauman P; Medical University of Gdansk, Gdansk, Poland.
  • Cieslewicz J; Department of Neurosurgery, Copernicus PL, Gdansk, Poland.
  • Grajkowska W; Department of Psychology and Sociology of Health and Public Health School of Public Health Collegium Medicum, University of Warmia - Mazury, Olsztyn, Poland.
  • Morosini N; Institute of Psychiatry and Neurology, Warsaw, Poland.
  • Noushmehr H; Faculty of Medical and Health Sciences, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland.
  • Wojtas B; Gdansk University of Technology, Faculty of Chemistry, Gdansk, Poland.
  • Kaminska B; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland.
Int J Cancer ; 153(5): 1003-1015, 2023 Sep 01.
Article in En | MEDLINE | ID: mdl-37338006
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Glioma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Int J Cancer Year: 2023 Document type: Article Affiliation country: Polonia Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Glioma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Int J Cancer Year: 2023 Document type: Article Affiliation country: Polonia Country of publication: Estados Unidos