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Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.
Promsote, Wanwisa; Xu, Ling; Hataye, Jason; Fabozzi, Giulia; March, Kylie; Almasri, Cassandra G; DeMouth, Megan E; Lovelace, Sarah E; Talana, Chloe Adrienna; Doria-Rose, Nicole A; McKee, Krisha; Hait, Sabrina Helmold; Casazza, Joseph P; Ambrozak, David; Beninga, Jochen; Rao, Ercole; Furtmann, Norbert; Birkenfeld, Joerg; McCarthy, Elizabeth; Todd, John-Paul; Petrovas, Constantinos; Connors, Mark; Hebert, Andrew T; Beck, Jeremy; Shen, Junqing; Zhang, Bailin; Levit, Mikhail; Wei, Ronnie R; Yang, Zhi-Yong; Pegu, Amarendra; Mascola, John R; Nabel, Gary J; Koup, Richard A.
Affiliation
  • Promsote W; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Xu L; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Hataye J; ModeX Therapeutics Inc., 22 Strathmore Road, Natick, MA, 01760, USA.
  • Fabozzi G; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • March K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Almasri CG; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • DeMouth ME; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Lovelace SE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Talana CA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • McKee K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Hait SH; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Casazza JP; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Ambrozak D; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Beninga J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Rao E; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Furtmann N; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Birkenfeld J; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • McCarthy E; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Todd JP; Perspix Biotech GmbH, FiZ Frankfurt Innovation Center Biotechnology, Altenhoeferallee 3, 60438, Frankfurt, Germany.
  • Petrovas C; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Connors M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Hebert AT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Beck J; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital (chuv) and University of Lausanne, Lausanne, Switzerland.
  • Shen J; NIAID, NIH, Bethesda, MD, 20892, USA.
  • Zhang B; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Levit M; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Wei RR; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Yang ZY; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Pegu A; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Mascola JR; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
  • Nabel GJ; ModeX Therapeutics Inc., 22 Strathmore Road, Natick, MA, 01760, USA.
  • Koup RA; Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.
Nat Commun ; 14(1): 3719, 2023 06 22.
Article in En | MEDLINE | ID: mdl-37349337

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido