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Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Randic, Tijana; Magni, Stefano; Philippidou, Demetra; Margue, Christiane; Grzyb, Kamil; Preis, Jasmin Renate; Wroblewska, Joanna Patrycja; Nazarov, Petr V; Mittelbronn, Michel; Frauenknecht, Katrin B M; Skupin, Alexander; Kreis, Stephanie.
Affiliation
  • Randic T; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg.
  • Magni S; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg.
  • Philippidou D; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg.
  • Margue C; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg.
  • Grzyb K; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg.
  • Preis JR; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg.
  • Wroblewska JP; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg.
  • Nazarov PV; Data Integration and Analysis Unit (DIA), Luxembourg Institute of Health, 1A-B, Rue Thomas Edison, 1445 Strassen, Luxembourg; Department of Cancer Research (DoCR), Luxembourg Institute of Health (LIH), Luxembourg, 6A, Rue Nicolas-Ernest Barblé, 1210 Luxembourg, Luxembourg.
  • Mittelbronn M; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg; Department of Cancer Research (DoCR), Luxembourg Institut
  • Frauenknecht KBM; National Center of Pathology (NCP), Laboratoire National de Santé (LNS), 3555 Dudelange, Luxembourg; Luxembourg Center of Neuropathology (LCNP), Dudelange, Luxembourg.
  • Skupin A; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg; Department of Cancer Research (DoCR), Luxembourg Institute of Health (LIH), Luxembourg, 6A, Rue Nicolas-Ernest Barblé, 1210 Luxembourg, Luxembourg; Department of Neuroscience, Un
  • Kreis S; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, 6, Avenue du Swing, 4367 Belvaux, Luxembourg. Electronic address: stephanie.kreis@uni.lu.
Cell Rep ; 42(7): 112696, 2023 07 25.
Article in En | MEDLINE | ID: mdl-37379213
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcriptome / Melanoma Limits: Humans Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country: Luxemburgo Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcriptome / Melanoma Limits: Humans Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country: Luxemburgo Country of publication: Estados Unidos