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Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting.
Greppmair, Sebastian; Brinkmann, Alexander; Roehr, Anka; Frey, Otto; Hagel, Stefan; Dorn, Christoph; Marsot, Amélie; El-Haffaf, Ibrahim; Zoller, Michael; Saller, Thomas; Zander, Johannes; Schatz, Lea Marie; Scharf, Christina; Briegel, Josef; Minichmayr, Iris K; Wicha, Sebastian G; Liebchen, Uwe.
Affiliation
  • Greppmair S; Department of Anaesthesiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
  • Brinkmann A; Department of Anaesthesiology and Intensive Care Medicine, General Hospital of Heidenheim, 89522, Heidenheim, Germany.
  • Roehr A; Department of Pharmacy, General Hospital of Heidenheim, 89522, Heidenheim, Germany.
  • Frey O; Department of Pharmacy, General Hospital of Heidenheim, 89522, Heidenheim, Germany.
  • Hagel S; Institute for Infectious Diseases and Infection Control, University Hospital, Friedrich-Schiller-University Jena, 07747, Jena, Germany.
  • Dorn C; Institute of Pharmacy, University of Regensburg, 93053, Regensburg, Germany.
  • Marsot A; Faculty of Pharmacy, University of Montréal, Pavillon Jean-Coutu, 2940 Chemin de Polytechnique, Montréal, QC, H3T 1J4, Canada.
  • El-Haffaf I; Faculty of Pharmacy, University of Montréal, Pavillon Jean-Coutu, 2940 Chemin de Polytechnique, Montréal, QC, H3T 1J4, Canada.
  • Zoller M; Department of Anaesthesiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
  • Saller T; Department of Anaesthesiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
  • Zander J; Laboratory Dr. Brunner, Laboratory Medical Care Center Konstanz GmbH, 78464, Constance, Germany.
  • Schatz LM; Department of Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Muenster, 48149, Muenster, Germany.
  • Scharf C; Department of Anaesthesiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
  • Briegel J; Department of Anaesthesiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
  • Minichmayr IK; Department of Clinical Pharmacology, Medical University Vienna, 1090, Vienna, Austria.
  • Wicha SG; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, 20146, Hamburg, Germany.
  • Liebchen U; Department of Anaesthesiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany. uwe.liebchen@med.uni-muenchen.de.
Intensive Care Med ; 49(8): 966-976, 2023 08.
Article in En | MEDLINE | ID: mdl-37439872
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperacillin / Critical Illness Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans Language: En Journal: Intensive Care Med Year: 2023 Document type: Article Affiliation country: Alemania
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperacillin / Critical Illness Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans Language: En Journal: Intensive Care Med Year: 2023 Document type: Article Affiliation country: Alemania