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S-Nitrosylation-mediated dysfunction of TCA cycle enzymes in synucleinopathy studied in postmortem human brains and hiPSC-derived neurons.
Doulias, Paschalis-Thomas; Yang, Hongmei; Andreyev, Alexander Y; Dolatabadi, Nima; Scott, Henry; K Raspur, Charlene; Patel, Parth R; Nakamura, Tomohiro; Tannenbaum, Steven R; Ischiropoulos, Harry; Lipton, Stuart A.
Affiliation
  • Doulias PT; Children's Hospital of Philadelphia Departments of Pediatrics and Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Chemistry and University Research Center of Ioannina, University of Ioannina, 45110 Ioannina, Greece.
  • Yang H; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Changchun University of Chinese Medicine, Changchun 130021, China.
  • Andreyev AY; Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Dolatabadi N; Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Scott H; Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • K Raspur C; Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Patel PR; Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Nakamura T; Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Tannenbaum SR; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Ischiropoulos H; Children's Hospital of Philadelphia Departments of Pediatrics and Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lipton SA; Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA. Electronic address: slipton@scripps.edu.
Cell Chem Biol ; 30(8): 965-975.e6, 2023 08 17.
Article in En | MEDLINE | ID: mdl-37478858
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Induced Pluripotent Stem Cells / Synucleinopathies Limits: Humans Language: En Journal: Cell Chem Biol Year: 2023 Document type: Article Affiliation country: Grecia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Induced Pluripotent Stem Cells / Synucleinopathies Limits: Humans Language: En Journal: Cell Chem Biol Year: 2023 Document type: Article Affiliation country: Grecia